GLP-1 receptor agonist medications include drugs FDA-approved for type 2 diabetes (since exenatide in 2005) and for chronic weight management (liraglutide / Saxenda in 2014), and they are available as a subcutaneous injection (most products) or as an oral tablet (Rybelsus only, as of April 2026)
For details on Hers compounded options, see our treatment section
The Lancet Neurology In the LEGATO-HD Phase 2 double-blind, placebo-controlled trial of laquinimod in patients with HD, laquinimod did not show a significant effect on motor symptoms assessed by the UHDRS-TMS but significantly reduced caudate volume loss compared with placebo at week 52
Hoshina Y, Hamamoto Y, Suzuki I, Nakajima T, Ida-Yonemochi H, Saku T
Jennifer Crystal is a writer and educator in Boston
The cost of your injections may also vary depending on the comprehensiveness of your treatment package