The Journal of clinical investigation 124, 42044211 (2014)
Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, et al: Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals
Coffee might not be ubiquitously beneficial (see this post for more on the pros and cons of coffee consumption), but the growing body of scientific literature explaining why coffee might prevent cancer shows that including coffee in an alternative protocol for treating cancer isnt a far-fetched idea
They are also used to treat fluid retention in patients with edema (swelling), cirrhosis, and heart failure
It also plays a role in immune function and mood regulation
These pharmacies can also supply essentially a copy of an FDA-approved drug when theres a shortage