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For these individuals, vitamin B12 injections are often the most effective way to restore healthy B12 levels because they bypass the digestive system entirely, delivering the vitamin directly into the bloodstream for maximum absorption (around 95% compared to 25-50% for oral supplements)

Frequency of Injections : The frequency of Vitamin B12 shots can also play a role in how quickly benefits are felt

A founder mutation in the PLPBP gene in families from Saguenay-Lac-St-Jean region affected by a pyridoxine-dependent epilepsy

Only after parents agreed to enroll their children in the study and signed informed consent, a detailed medical history, current drug/supplement intake, and some demographic information about the child and parents were collected