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CAFs-derived exosomes include lactate, acetate, amino acids, TCA cycle metabolites like succinate, and lipids

These non-toxic nanocarriers influence immunological function, inhibit tumor growth, and show promise as therapeutic agents, although rigorous quality control, standardized isolation methods, and consideration of dietary influences are crucial for their clinical application [234]

J., Greenhaff, P

But those same receptors exist elsewhere in body, including the liver and the pancreas

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