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The pathological status and healing process of wounds were evaluated by H&E staining and Massons trichrome staining
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If Phase III data support approval, and early signals for both are positive, TGA registration applications could follow
injection with 100 nmol kg 1 MK-801 ( n = 7 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice) or vehicle (isotonic saline, n = 8 mice) in lean mice
Different trials, different populations, different durations, so the figures below are averages from the main pivotal trials, not head-to-head results
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