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Why NAD+ Declines with Age As you age, NAD+ levels naturally decrease due to: Increased oxidative stress DNA damage accumulation Reduced production efficiency This decline is linked to fatigue, cognitive slowdown, and decreased cellular resilience

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It is commonly suggested to help the body generate energy at a cellular level, especially when normal diet and nutrient levels fall short

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Elevated ROS levels exert a paradoxical effect: while excessive ROS can be cytotoxic, moderate overproduction contributes to tumorigenesis by inflicting oxidative damage on DNA