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Vehicle-control MIA mice exhibited no significant change in social novelty, with pre-vehicle scores of 9.1 2.6 and post-vehicle scores of 0.13 4.2, p = 0.23 (Fig 2B)

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52 Cellular stress, such as DNA damage, hypoxia, and oncogene activation, disturbs the interaction between p53 and MDM2 and inhibits p53 degradation, resulting in p53 accumulation

doi: 10.1002/jmv.27405 181 MarM.de GregorioE.de DiosC.Roca-AgujetasV.CucarullB.TutusausA.et al

doi: 10.21037/atm-21-5849, 57