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A 2003 research paper, conducted on mice, showed that topical Pycnogenol (used at 0.05-0.2%) has the potential to provide photoprotection for humans in a complementary role to sunscreens
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doi: 10.1007/s11626-018-0310-2 240 ZhaoFDongJGuoJBiL
Another physical indicator is decreased urine output
& Ponce, D
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