patent applications and been granted 16 patents related to these two products
Epitalon has been shown to significantly increase the expression of key antioxidant enzymes: Superoxide dismutase (SOD-1) Catalase NAD(P)H quinone dehydrogenase 1 (NQO1) These effects are mediated via the Keap1/Nrf2 signaling pathway [40, 41]: a master regulator of cellular redox balance
Others require careful adjustments throughout treatment stages, if intolerable side effects occur, or due to pre-existing conditions, such as PCOS or thyroid disorders
Mol Cell Biochem 293:16171, PMID: 16786188 Yang Y, Cheng JZ, Singhal SS, Saini M, Pandya U, Awasthi S, Awasthi YC (2001) Role of glutathione S -transferases in protection against lipid peroxidation
Courouss T, Gautron S (2015) Role of organic cation transporters (OCTs) in the brain
Work: 2.1