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Enzyme function is also compromised by copper deficiency, including that of copper-zinc SOD (Cu-Zn SOD), resulting in a weakened antioxidant defence system and increased vulnerability to oxidative stress, contributing to the development of atherosclerosis (103)

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During the loading phase , patients typically receive 1mg of hydroxocobalamin intramuscularly three times per week for two weeks (six injections total)

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