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PMC 11948232
The main purpose of the expansion triggered by activation and cytokines is to increase and enrich T cell numbers, and at the same time eliminate non-T cells by exposing them to culture conditions that are suboptimal to other cell types
The problem: natural GLP-1 lasts only a couple of minutes before enzymes break it down
| Penn Medicine
Early neuroimaging studies indicate that liraglutide might reduce activation in brain regions associated with food reward when participants view images of palatable foods
Quantitative and regional differences in human versus rodent GLP-1R distribution mean that circuit-level effects observed in mice may not map cleanly onto human neurobiology, even if the underlying pharmacology is conserved
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