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Patients should be advised about the urine discoloration (to avoid alarm) and counseled to report any persistent side effects
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Recent developments include CMS unveiling its BALANCE model, a voluntary Medicare and Medicaid coverage pathway that includes price negotiations and supplemental lifestyle support, with coverage beginning in 2026 for Medicaid and 2027 for Medicare Part D [2]
Knowing this temporary nature helps users push through the adjustment period rather than discontinuing prematurely
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Poor gastrointestinal tolerance and malnutrition caused by appetite suppression, as well as micronutrient deficiencies, may exacerbate muscle loss
