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The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia

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View study on ResearchGate Reduced Osteoarthritis Risk A large-scale analysis published in 2024 reported that patients using Tirzepatide were significantly less likely to develop osteoarthritis than those on other weight-loss medications

Never store pens with needles attached, as this can cause air bubbles, medication leakage, or needle contamination

Health Technology Assessment, 28 (43), 1210

These include: Lack of efficacy: Despite the medications effectiveness for many individuals, it may not produce the desired blood sugar control or weight loss in some cases