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Tirzepatide is a large protein molecule

CJC-1295, Sermorelin, and Tesamorelin bind GHRH receptors on pituitary somatotroph cells, prompting the pituitary to release its own growth hormone in a pulsatile pattern that raises downstream IGF-1

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However, these drugs are not subject to the same rigorous testing and approval process as FDA-approved medications, which raises significant concerns about their safety, effectiveness, and quality

For now, researchers are making decisions based on incomplete but generally encouraging data

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