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A cross-sectional study of GLP-1 users found significant shortfalls in calcium, iron, magnesium, potassium, vitamins A, C, D, and E, plus choline
Semaglutide acts on the GLP-1 pathway alone, while Tirzepatide activates both the GLP-1 and GIP pathways for a combined effect on appetite control, fullness, and metabolic support
Individuals with history of pancreatitis Those with a prior history of pancreatitis face elevated risk with any hormonal weight loss compound that affects pancreatic function
Additionally, patients looking to use insurance will be disappointed
The main NRF2-activating drug candidates that have been explored, and many of which have reached different stages of clinical trials, are presented in Table 1
