With France joining the UK, Switzerland, Japan, and the United States in advancing insurance reimbursement for obesity drugs within public healthcare programs, obesity is increasingly being recognized not as a matter of individual lifestyle choices but as a chronic disease requiring state management
However, when these systems become imbalanced, low-grade systemic inflammation perpetuates metabolic alterations by establishing a cycle that leads to pathological processes such as insulin resistance, atherosclerosis and endothelial dysfunction that underlie a variety of diseases 37,38,39
11 mg/dL, respectively)
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Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, and Semaglutide, a GLP-1 RA, have shown greater weight loss efficacy than traditional medications like Phentermine/Topiramate (Qsymia), Naltrexone/Bupropion (Contrave), and Phentermine 12,14,15
Healthcare providers conduct comprehensive assessments, considering the potential benefits and risks