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An x-ray of the wrist and hand may be obtained to evaluate for contributions from prior injuries or arthritis

If you're unsure about injection procedures, a clinician can provide guidance

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Vaccaro O, Masulli M, Nicolucci A et al (2017) Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial

For systemic or musculoskeletal targets, injectable has a pharmacokinetic advantage