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That's not particularly surprising: many users say the regular injections (under the skin) are inconvenient and that the injections are painful with needles that are too large

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Keep things lighter, especially during those first few days after a dose escalation, says Denise Hernandez, a registered dietitian and Food Data Curator with MyFitnessPal

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Increased body fat in the upper chest and obliques Abdominal weight gain Lethargy/fatigue Brain fog Mood swings Irritability Low libido Depression Anxiety Long term, excess estrogen in men can trigger abnormal cell growth and prostate enlargement