Receptors for GIP and GLP-1 have been identified in brain regions involved in the regulation of appetite, satiety, food/energy intake and energy expenditure [6] Fig
Diabetics who take metformin may have low B12 levels as a side effect of the drug
Semaglutide carries a serious warning about thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), based on animal studies
Our previous work highlights the importance of prioritising nutrient-dense foods including high-quality protein intake, ideally distributed evenly across meals, to help preserve lean mass during periods of reduced appetite and rapid weight loss. While there was insufficient evidence from the studies to recommend strict low-fat diets to complement the weight loss drugs, some observational studies found that people on the treatments often consumed excessive levels of total and saturated fat
Even after stopping the weight loss medications, symptoms persisted, and they were later diagnosed with SIBO (3)
Phase 3 The TRIUMPH Program This is where it gets real