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2006;291(6):E1290-E1294

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Perhaps, these findings are explained by the well-established acute nature of APAP-induced hepatotoxicity and elevated tolerance of female mice

Inhibition of the glycolytic key enzyme LDHA or use of LDH inhibitors (such as sodium oxalate) can enhance CD8 + T cell killing ability, reverse tumor immune escape, and produce a synergistic effect with anti-PD-1 therapy