The approval is supported by data from the Phase I/II TRIDENT-1 trial, where treatment with Augtyro resulted in a 58% confirmed objective response rate (cORR) in TKI-nave patients, of which 15% were complete responses
Nausea is the most common GI side effect
These byproducts may include: Ketones (from fat burning) Urea and ammonia (from protein breakdown) Other organic compounds filtered by the kidneys If more of these substances are present in the blood, they will appear in urine and may affect its smell
Based on the weight-loss correlation data, one would expect hair loss rates to be at least comparable to or potentially higher than those seen with semaglutide and tirzepatide
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Since GLP-1 receptor agonists work by slowing gastric emptying, they can lead to side effects like nausea, vomiting, constipation, and diarrhea