They help your body process fat more efficiently, support liver health during weight loss, and can reduce some of the fatigue that comes with caloric restriction
So, a 200-pound person may lose 10 pounds or more on the 10 mg dose in 72 weeks (just over a year)
The lower activity of ChaC2 may be partly attributed to flexible loop 2, acting as a gating function to achieve specificity for GSH binding and regulate a constant GSH degradation rate
But many clinicians extrapolate dosing patterns to weight loss, always proceeding cautiously
On weight loss, there is not
Common side effects include nausea, vomiting, constipation, and mild diarrhea, especially during dose escalation