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The efficacy of biotherapeutic agents is higher than that of conventional methods, but there are still some side effects, such as instability, low bioavailability, high rate of infection, in particular lymphomas [26]

Realizing this growing need for fair skin, many pharmaceutical companies are developing different molecules for skin lightening

By inhibiting the enzyme, the skin no longer produces pigmentation

In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg-40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12

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