Caren Mangarelli, a pediatrician who works with the Lurie Childrens Hospital's Pediatric Wellness & Weight Management Program, told ABC News that she believes the medications are only reaching a small percentage of teens who could potentially benefit from the drug, whether for type 2 diabetes and/or obesity, citing the statistic that nearly 20%, or around 14.7 million children and adolescents ages 2 to 19 in the U.S
Providers consider factors such as medical history, weight loss goals, side effect tolerance, and overall metabolic health before recommending treatment
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GIP receptor activation adds a second insulin secretion signal and may independently influence fat metabolism
While inter-individual variability in HRV is high, consistent tracking especially through validated wearables during periods of rest or sleep allows for meaningful trend analysis