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I share this story with patients not just because it is fascinating, but because it often shifts how they think about these medications

The complete selection process, including the number of records identified, screened, and excluded with explicit reasons (separated for preclinical and clinical/epidemiological literature), is documented in the PRISMA flow diagram (Figure 1)

We are aware there can be positive mental health and physical impacts of these medications and they can be very beneficial for some people