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Large trials like SELECT, STEP, and PIONEER 7 suggest that with proper medical oversight, semaglutide can be used safely over months or even years

Another concern is side effects

Food and Drug Administration (FDA), unintentional overdose is a leading cause of acute liver failure due to individuals exceeding the recommended dose without realizing the dangers

This is a trial starting dose, not an approved patient dose

"Based on the evidence available today, I think it would be premature to assume GLP-1 medications are headed toward prohibition," Gross said

The goal is not just to know whether GLP-1s work but whether consumers stay on them long enough for the system to see measurable returns