JAMA Internal Medicine analyzed 18,386 matched pairs in a retrospective EHR cohort and found tirzepatide at 15.3% and semaglutide at 8.3% weight loss at 12 months
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Weight loss results: head-to-head data comparison No direct head-to-head trial between survodutide and tirzepatide has been conducted
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3 However, the short half-life of native GLP-1 has limited its therapeutic use for diabetes