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It was showed that NP4 treatment leaded to an increase in pro-inflammatory M1-type macrophages and a decrease in anti-inflammatory M2-type macrophages in mouse tumor tissues, with the proportion of M1 to M2 macrophages being 4.4 times higher compared to untreated mouse tumor tissues (Fig

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But a 10mg retatrutide vial at a 1-2mg starting dose will need multiple needle insertions over several weeks

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Cells were incubated with base assay medium