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To elaborate, increased levels of oxidized lipids (6), oxidized proteins (7), and oxidized DNA (7) and decreased levels of reduced glutathione (8) have been demonstrated in PD substantia nigra

10-Steven Johnsons syndrome Steven Johnson's syndrome is a severe and rare reaction resulting from medication use

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[6] [7] [10] GPx1 typically uses glutathione (GSH) as the reductant, but when glutathione synthetase (GSS) is, as in brain mitochondria, -glutamylcysteine can serve as the reductant instead

10.1002/adma.201802244 74 XiongY.-X.XiaoC.LiZ.-F.YangX.-L