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(5) Routine dietary biotin generally does not reach interfering levels, but high-dose cosmetic or therapeutic supplements can

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This includes vegans and vegetarians, older adults, individuals with atrophic gastritis, pernicious anemia, gastrointestinal disorders, those who have had gastrointestinal surgery and people who take certain medications including, but not limited to, estrogen (HRT), and birth control pills

Older adults, people with digestive issues, and vegans are at a higher risk of developing a Vitamin B-12 deficiency