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The cerebrovasculature is a very bioenergetically active tissue with capillary endothelial cells having been shown to possess five times more mitochondria than muscle cells (Oldendorf and Brown, 1975) and transport 10 times their weight in glucose each minute across the BBB, along with accomplishing other energetically costly cellular processes (Cunnane et al., 2011)

Koehler H et al (2021) Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis

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this nutrient molecule can also be found in a variety of food sources

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Should future research validate its advantages, it may eventually be utilized in conjunction with stem cell therapy, tailored scaffolds, or alternative biomaterials to augment healing [4][3]