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AOD9604 and Oral Bioavailability Research Pharmacokinetic profiling in pigs confirmed that AOD9604 is orally bioavailable, with intact peptide and its principal N-terminal truncation degradants (2aa and 3aa fragments) detected in plasma following oral dosing

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"Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review." Pharmaceutics , 2023