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Presented for research literature review only Li NQ et al

It has many roles, including supporting the actions of vitamins C and E, neutralising chemical toxins and transporting mercury

Depletion of cellular GSH by using buthionine sulfoxamine (BSO), which inhibits glutamatecysteine ligase (the rate-limiting enzyme for GSH synthesis) is sufficient to induce ferroptosis due to impaired cellular antioxidant capacity 18

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