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MOF-mediated acetylation enhances NRF2 nuclear retention and downstream gene transcription, playing a critical role in antioxidant responses and drug resistance, and regulating tumor growth and resistance through an NRF2-dependent mechanism [58]

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When expressed as a percentage increase in comparison to a placebo (1.31mIU/l or 0.4ng/ml), this augmentation appears to surpass 60-fold