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Huang BS et al

Chase a goal down one road and the body reroutes around it

This is a hypothesis-level consideration that has driven comparative research

The rabbits were randomly divided into three treatment groups of six animals each: a TCC group, a zinc oxide group, and a no-treatment control group

Onset varies with age, baseline tissue health, and protocol consistency

Examples of drugs that exhibit flow dependent hepatic clearance (high hepatic extraction ratio) include: Morphine , Lidocaine, Verapamil, Nitroglycerin, Propranalol Flow-Dependent Clearance The clearance of high-extraction drugs is primarily dependent on hepatic blood flow