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Although LA can reduce hepatic fatty accumulation and SAT/PUFA ratios to a great extent, the effects of LA on reducing liver steatosis in gene-mutant obesity may be influenced by the high levels of cholesterol or TG present in the diet

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Patients should contact their healthcare provider if diarrhea persists beyond a few days despite dietary modifications and supportive care, or if symptoms significantly interfere with daily activities and quality of life

Aggregation is the primary concern

"Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme." Trends in Endocrinology & Metabolism

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