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It only becomes toxic when metabolized into NAPQI
This is because vitamin B12 plays an important role in helping your cells use nutrients and perform metabolic functions
GAD67 is encoded by the GAD1 gene and expressed in the neuronal soma or throughout the entire neuron, whereas GAD65 is encoded by the GAD2 gene and expressed at axon terminals
A Phase 3 diabetes trial is also ongoing as part of the submission package
Long-term safety concerns are lower than for compounds that introduce entirely foreign mechanisms
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinsons disease
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