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The preclinical literature supports this framing
10.1182/blood-2013-01-480129 193 Nayak-KapoorA.HaoZ.SadekR.DobbinsR.MarshallL.VahanianN
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Continuous use increases side effect risk and promotes desensitization
According to Brecka, by around age 50, levels can drop by roughly half
Access this article Similar content being viewed by others References Teede HJ, Misso ML, Costello MF, et al
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