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Physical examination may reveal pallor, glossitis, neurological signs such as reduced vibration sense or proprioception, and in advanced cases, ataxia or cognitive impairment

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Cobalamin is another word for Vitamin B12

(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature

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Vitamin B6 is needed to make serotonin and dopamine, the brain chemicals that help you feel happy and motivated