They can also be prescribed for weight loss in individuals who are overweight or obese, particularly when diet and exercise alone have not been effective
Who can get it: Ozempic and Rybelsus require a diagnosis of type 2 diabetes (although Ozempic can be prescribed off-label for weight loss), while Wegovy requires either a BMI of 30 or a BMI of at least 27 plus another weight-related ailment (like high blood pressure or obstructive sleep apnea)
Based on these results, Eli Lilly plans to submit an application to the FDA in mid-2024 to get tirzepatide approved as a sleep apnea treatment
As of now, available data suggest both drugs are highly effective, with ongoing research needed to solidify which might generally lead
In the EMPA-REG OUTCOME trial , empagliflozin reduced cardiovascular death by 38% in high-risk type 2 diabetes patients (Zinman et al., 2015)
The influence of GLP-1 on the glucose-induced insulin secretion: effects on beta cell sensitivity in type 2 diabetic patients and controls