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Stimulation targets were individualized based on personalized functional networks on the precentral gyrus identified using the patients pretreatment scans

The kidney and brain tissues were analyzed using conventional biochemical tests to assess oxidative stress and inflammatory responses

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While large-scale randomized trials in MCAS are limited, case-report literature describes improvement in patients with overlapping conditions such as MCAS and severe postural orthostatic tachycardia syndrome (POTS) when naltrexone was included as part of a comprehensive care plan

In contrast, 300 mg/d of reduced CoQ 10 noticeably improved symptoms in specific PD populations, such as patients with the wearing-off phenomenon (209)