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Glutathione reduces disulfide bonds formed within cytoplasmic proteins to cysteines by serving as an electron donor
The biocompatibility, targeting, and release mechanisms of nanoparticles need to be further studied, and the safety and efficacy of CRISPR technology in periodontal therapy, especially in avoiding genetic variation, need to be further explored
Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven
In cases where contamination occurred due to poor technique, injection site reactions may also appear
& Hori, Y