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In malignant melanoma, USP8 mRNA and protein expression levels are higher than in normal melanocytes
This pseudo-substrate might be involved in the modulation of substrate access to the active site, which might suggest a possible auto-regulatory role, in line with the documented roles of pseudo-substrates in the regulation of kinases 48
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Nonetheless, both agents successfully counteracted the CARB-induced reduction in AMH, thereby contributing to the maintenance of follicular reserve
Reducing inflammation at the cellular level, it creates an optimal environment for tissue repair and regeneration
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