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dosing with 2 g/kg glucose in 48-week old female WT and KO mice (n = 7 each group)
(*NICE guidelines are evidence-based recommendations from the National Institute for Health and Care Excellence for health and social care in England and Wales)
GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety
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Manufacturer guidance recommends against use during lactation due to this evidence gap, not proven harm
No, GLP-1 medications are not controlled substances and do not appear on standard employment drug screenings, which test for substances of abuse like opioids, amphetamines, and cannabis
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