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By blocking NNMT, 5-Amino-1MQ prevents NAD+ breakdown , allowing its levels to rise

Rare adverse effects specific to cyanocobalamin may include mild transient diarrhea, particularly with initial doses, and very rarely, allergic reactions in sensitive individuals

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For our body to properly absorb it, the stomach needs to have sufficient acid to perform the removal, a process that is not always completed successfully due to the lack of something called the intrinsic factor

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They are not a recommendation for human use