[13] Zhang, D., et al
This is a concern, particularly for those trying to improve their overall body composition or for individuals with diabetes, where muscle mass plays a vital role in insulin sensitivity
Overall serious adverse events were actually reduced in semaglutide users compared to controls, with a relative risk of 0.92 (p = 0.005)
Kendall DM, Riddle MC, Rosenstock J, et al
But there are more serious side effects that include: Kidney problems, severe allergic reactions, and an increased risk of skin cancer, especially in people with pre-existing skin conditions (there have been reports of Melanoma diagnosis within four weeks of using Melanotan)
However, levels can drop with age, stress, poor diet, alcohol use, and toxin exposure