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The combination may significantly amplify these symptoms, potentially leading to dehydration, electrolyte imbalances, and reduced medication adherence

14.2 Monotherapy Use of MOUNJARO in Adult Patients with Type 2 Diabetes Mellitus SPL UNCLASSIFIED SECTION SURPASS-1 (NCT03954834) was a 40-week double-blind trial that randomized 478 adult patients with type 2 diabetes mellitus with inadequate glycemic control with diet and exercise to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg, or placebo once weekly

The active compound is the same regardless of how you take it, and both methods have solid evidence behind them

These effects are mainly relevant if youre living with type 2 diabetes and take Mounjaro alongside insulin or a sulphonylurea, the two diabetes drug classes that carry a meaningful low blood sugar risk

Risk: Cumulative effects can be unpredictable

But we need time to develop a strategy for making access to GLP-1 drugs affordable, McCarthy said