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Zinman B, Aroda VR, Buse JB, Cariou B, Harris SB, Hoff ST, et al

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However, reperfusion can cause further damage to cardiac tissue, including cytokine production, neutrophil infiltration, and ROS production, called I/R injury [89]

It gives you a number, and that number gets you placed into a category underweight, normal, overweight, obese, severely obese

FDA approval exists precisely because regulators reviewed that kind of trial data