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Potentially severe side effects of Trulicity: Hypoglycemia Gastroparesis (stomach paralysis) Ileus (intestinal blockage) Gallbladder disease Kidney damage Pancreatitis Thyroid tumors (Trulicity carries a boxed warning of thyroid tumors after studies showed an increased risk in animals, but had unclear implications for humans) Allergic reactions Signs and symptoms of serious side effects may include severe abdominal pain, persistent nausea, vomiting, fever, dark urine, or signs of an allergic reaction

Why rotation prevents absorption problems Injecting repeatedly in the same spot causes localized tissue changes

Compare this to peptides like GHK-Cu which repair damage after it occurs

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Therefore, elevated glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) keeps its substrate 3-PG to a relatively low level and promotes the PPP in cancer cells (91)