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528 CQ also modulates the expression and activity of the transcription factor Nurr1, which influences Treg differentiation, providing an additional mechanistic link between autophagy-related pathways and immune tolerance

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10.1002/pmic.200600443 74 MarchandC.Le MarechalP.MeyerY.Miginiac-MaslowM.Issakidis-BourguetE.DecottigniesP

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Both strategies appear to enhance weight loss beyond GLP-1 agonism alone, raising fundamental questions about GIP receptor biology in obesity